Description Usage Arguments Value References See Also Examples
View source: R/normalization.R
ZScore normalization (see Value and References)
1 |
header |
the header of a dataset file generated with |
dataset |
an R data frame generated with |
listOfArgs |
a list containing: - a character string specifying the column whose values will be used for normalization - a flag specifying whether controls should be excluded for the computation of the median and median absolute deviation (1) or not (0). |
The ZScore is defined as the quotient of the difference between an intensity value and the median of the plate, and of the median absolute deviation.
Returns a list containing:
header |
The new header (with an added entry about the normalization procedure in the comments) |
dataset |
The new dataset with normalized values. The old values are saved in an extra column of the dataset with the suffix ".old" |
N. Malo et al. Statistical practice in high-throughput screening data analysis. Nature Biotech, 24(2): 167-175, 2006.
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