Description Constructor Author(s)
The parameters are used by the absoluteCN function.
GCAdjustParams(genome, mappability, min.mappability, n.bins = NULL,
min.bin.size = 1, poly.degree = NULL, ploidy = 1)
Creates a GCAdjustParams object.
genomeA BSgenome object of the
species that the experiment was done for.
mappabilityA BSgenome object,
or the path to a FASTA file generated by
GEM mappability containing the mappability of
each base in the genome.
min.mappabilityA number between 0 and 100 that is a cutoff on window mappability.
n.binsThe number of GC content bins to divide the windows into, before finding the mode of counts in each window.
min.bin.sizeGC bins with less than this many count windows inside them will be ignored.
poly.degreeThe degree of the polynomial to fit to the GC bins' count modes.
ploidyA vector of multipliers to use on the estimated absolute copy number of each sample, if the number of sets of chromosomes is known.
Dario Strbenac
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