bacon: Controlling bias and inflation in association studies using the empirical null distribution

Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.

AuthorMaarten van Iterson [aut, cre], Erik van Zwet [ctb]
Date of publicationNone
MaintainerMaarten van Iterson <mviterson@gmail.com>
LicenseGPL (>= 2)
Version1.2.0
https://github.com/mvaniterson/bacon

View on Bioconductor

Files in this package

bacon/DESCRIPTION
bacon/NAMESPACE
bacon/NEWS
bacon/R
bacon/R/BaconClass.R bacon/R/BaconMethods.R bacon/R/bacon.R bacon/R/normmixture.R
bacon/build
bacon/build/vignette.rds
bacon/inst
bacon/inst/CITATION
bacon/inst/doc
bacon/inst/doc/bacon.R
bacon/inst/doc/bacon.Rmd
bacon/inst/doc/bacon.html
bacon/man
bacon/man/Bacon-class.Rd bacon/man/bacon.Rd bacon/man/bias-methods.Rd bacon/man/dnormmix.Rd bacon/man/es-methods.Rd bacon/man/estimates-methods.Rd bacon/man/fit-methods.Rd bacon/man/inflation-methods.Rd bacon/man/meta-methods.Rd bacon/man/plot-Bacon-method.Rd bacon/man/plotnormmix.Rd bacon/man/posteriors-methods.Rd bacon/man/pval-methods.Rd bacon/man/rnormmix.Rd bacon/man/se-methods.Rd bacon/man/topTable-methods.Rd bacon/man/traces-methods.Rd bacon/man/tstat-methods.Rd
bacon/src
bacon/src/Rinit.c
bacon/src/bacon.c
bacon/tests
bacon/tests/testthat
bacon/tests/testthat.R
bacon/tests/testthat/test_estimates.R
bacon/vignettes
bacon/vignettes/bacon.Rmd
bacon/vignettes/bacon.bib

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

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