Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.
|Author||Maarten van Iterson [aut, cre], Erik van Zwet [ctb]|
|Bioconductor views||BatchEffect Bayesian GenomeWideAssociation MethylationArray MultipleComparison RNASeq Regression StatisticalMethod Transcriptomics|
|Maintainer||Maarten van Iterson <[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on Bioconductor|
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