birta-package: Joint Bayesian Inference of miRNA and Transcription Factor...
In birta: Bayesian Inference of Regulation of Transcriptional Activity
Description
Details
Author(s)
References
Description
Expression levels of mRNA molecules are regulated by different processes, comprising inhibition or activation by transcription factors and post-transcriptional degradation by microRNAs. birta uses the regulatory networks of TFs and miRNAs together with mRNA and miRNA expression data to predict switches in regulatory activity between two conditions. A Bayesian network is used to model the regulatory structure and Markov-Chain-Monte-Carlo is applied to sample the activity states.
Details
Package: birta
Type: Package
Version: 0.99.1
Date: 2012-03-6
License: GNU GENERAL PUBLIC LICENSE (GPL) >= 2
LazyLoad: yes
Author(s)
Benedikt Zacher, Khalid Abnaof, Stephan Gade, Erfan Younesi, Achim Tresch, Holger Frohlich
Maintainer: Benedikt Zacher <zacher@lmb.uni-muenchen.de>
References
B. Zacher, K. Abnaof, S. Gade, E. Younesi, A. Tresch, and H. Frohlich. Joint Bayesian Inference of Condition Specific miRNA and Transcription Factor Activities from Combined Gene and microRNA Expression Data. submitted, 2012.
birta documentation built on April 28, 2020, 7:27 p.m.
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Description Details Author(s) References
Description
Expression levels of mRNA molecules are regulated by different processes, comprising inhibition or activation by transcription factors and post-transcriptional degradation by microRNAs. birta uses the regulatory networks of TFs and miRNAs together with mRNA and miRNA expression data to predict switches in regulatory activity between two conditions. A Bayesian network is used to model the regulatory structure and Markov-Chain-Monte-Carlo is applied to sample the activity states.
Details
| Package: | birta |
| Type: | Package |
| Version: | 0.99.1 |
| Date: | 2012-03-6 |
| License: | GNU GENERAL PUBLIC LICENSE (GPL) >= 2 |
| LazyLoad: | yes |
Author(s)
Benedikt Zacher, Khalid Abnaof, Stephan Gade, Erfan Younesi, Achim Tresch, Holger Frohlich Maintainer: Benedikt Zacher <zacher@lmb.uni-muenchen.de>
References
B. Zacher, K. Abnaof, S. Gade, E. Younesi, A. Tresch, and H. Frohlich. Joint Bayesian Inference of Condition Specific miRNA and Transcription Factor Activities from Combined Gene and microRNA Expression Data. submitted, 2012.
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