bgAdjust: Remove background

Description Usage Arguments Details Value Author(s) Examples

Description

Estimate and remove background signal using anti-genomic background probes

Usage

1

Arguments

dat

a TilingFeatureSet

copy

Only relevant when using disk-backed objects. If TRUE a copy will be made leaving the original object (dat) unchanged. The input object will not be preserved if copy=FALSE

Details

Background signal removal using a modified version of the RMA convolution model. The background signal level is estimated within GC-strata using anti-genomic background probes.

Value

a TilingFeatureSet

Author(s)

Martin Aryee <aryee@jhu.edu>

Examples

1
# See normalizeBetweenSamples

charm documentation built on May 6, 2019, 2:29 a.m.