spatialAdjust: Correct spatial artifacts

Description Usage Arguments Details Value Author(s) Examples

Description

Remove spatial artifacts from microarray data stored in TilingFeatureSet objects

Usage

1
spatialAdjust(dat, copy=TRUE, blockSize, theta = 1)

Arguments

dat

TilingFeatureSet

copy

Only relevant when using disk-backed objects. If TRUE a copy will be made leaving the original object (dat) unchanged. The input object will not be preserved if copy=FALSE

blockSize

The array is divided into a series of blockSize x blockSize rectangular blocks and the average signal level calculated for each. If blockSize is unspecified a size is chosen that gives about 1250 probes per block.

theta

smoothing parameter

Details

The array is divided into a set of blockSize x blockSize squares. A kernel smoother is then used to even out spatial artifacts.

Value

a TilingFeatureSet

Author(s)

Martin Aryee <aryee@jhu.edu>

Examples

1
# See normalizeBetweenSamples

charm documentation built on May 6, 2019, 2:29 a.m.