Penalized least squares regression is applied to fit piecewise constant curves to copy number data to locate genomic regions of constant copy number. Procedures are available for individual segmentation of each sample, joint segmentation of several samples and joint segmentation of the two data tracks from SNP-arrays. Several plotting functions are available for visualization of the data and the segmentation results.
|Author||Gro Nilsen, Knut Liestoel and Ole Christian Lingjaerde.|
|Bioconductor views||CopyNumberVariation Genetics SNP Visualization aCGH|
|Maintainer||Gro Nilsen <[email protected]>|
|Package repository||View on Bioconductor|
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