epiScreen: Analyse large double knock-out screen.

In epiNEM: epiNEM

Description

This function is used to analyse knock-out screens with multiple double and single knock-outs combined in one data set.

Usage

epiScreen(data, ...)

Arguments

data	data matrix containing multiple single and double kock-downs in columns and effect reporters in the rows
...	additional parameters, e.g. for the main epiNEM function

Value

list object with vectors of double knock-downs, single knock-downs and two matrices with doubles in the columns and singles in the rows. The first matrix denotes the respective logical gate for the triple and the second matrix the log-likelihood

Author(s)

Martin Pirkl

Examples

data <- matrix(sample(c(0,1), 100*9, replace = TRUE), 100, 9)
colnames(data) <- c("A.B", "A.C", "B.C", "A", "B", "C", "D", "E", "G")
rownames(data) <- paste("E", 1:100, sep = "_")
res <- epiScreen(data)

epiNEM documentation built on Nov. 8, 2020, 6:51 p.m.