methylKit: DNA methylation analysis from high-throughput bisulfite sequencing results

methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods and whole genome bisulfite sequencing. It also has functions to analyze base-pair resolution 5hmC data from experimental protocols such as oxBS-Seq and TAB-Seq. Methylation calling can be performed directly from Bismark aligned BAM files.

Package details

AuthorAltuna Akalin [aut, cre], Matthias Kormaksson [aut], Sheng Li [aut], Arsene Wabo [ctb], Adrian Bierling [aut], Alexander Gosdschan [aut]
Bioconductor views DNAMethylation MethylSeq Sequencing
MaintainerAltuna Akalin <aakalin@gmail.com>, Alexander Gosdschan <alex.gos90@gmail.com>
LicenseArtistic-2.0
Version1.16.1
URL http://code.google.com/p/methylkit/
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methylKit")

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methylKit documentation built on Jan. 30, 2021, 2 a.m.