Description Usage Arguments Value Author(s) Examples

View source: R/calcFactornew.R

Amends of TMM normalization for our methond.

1 2 | ```
calcFactornew(obs, ref, m, k, logratioTrim=.3, sumTrim=0.05,
doWeighting=TRUE, Acutoff=-1e10)
``` |

`obs` |
Counts of treatment sample. |

` ref` |
Counts of control sample. |

`m` |
The number of CpG in each bin. |

`k` |
The number of MRE-CpG in each bin. |

`logratioTrim` |
amount of trim to use on log-ratios ("M" values) |

`sumTrim` |
amount of trim to use on the combined absolute levels ("A" values) |

`doWeighting` |
logical, whether to compute (asymptotic binomial precision) weights |

`Acutoff` |
cutoff on "A" values to use before trimming |

A real value larger than 0.

Yan Zhou, Bo Zhang, Nan Lin, BaoXue Zhang and Ting Wang

1 2 3 4 5 |

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