netReg: Network-Regularized Regression Models

netReg fits linear regression models using network-penalization. Graph prior knowledge, in the form of biological networks, is being incorporated into the loss function of the linear model. The networks describe biological relationships such as co-regulation or dependency of the same transcription factors/metabolites/etc. yielding a part sparse and part smooth solution for coefficient profiles.

Package details

AuthorSimon Dirmeier [aut, cre]
Bioconductor views FeatureExtraction GraphAndNetwork Network Regression Software StatisticalMethod
MaintainerSimon Dirmeier <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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netReg documentation built on Nov. 8, 2020, 5:17 p.m.