rqt: rqt: utilities for gene-level meta-analysis

Despite the recent advances of modern GWAS methods, it still remains an important problem of addressing calculation an effect size and corresponding p-value for the whole gene rather than for single variant. The R- package rqt offers gene-level GWAS meta-analysis. For more information, see: "Gene-set association tests for next-generation sequencing data" by Lee et al (2016), Bioinformatics, 32(17), i611-i619, <doi:10.1093/bioinformatics/btw429>.

Package details

AuthorI. Y. Zhbannikov, K. G. Arbeev, A. I. Yashin.
Bioconductor views GenomeWideAssociation PrincipalComponent Regression Sequencing StatisticalMethod Survival
MaintainerIlya Y. Zhbannikov <ilya.zhbannikov@duke.edu>
URL https://github.com/izhbannikov/rqt
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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rqt documentation built on Nov. 8, 2020, 4:50 p.m.