median_replicates: median_replicates

In scsR: SiRNA correction for seed mediated off-target effect

Description

perform the median of the replicates (i.e. group by oligo sequence and takes the median of the score value ).

Usage

median_replicates(screen, seedColName = "seed7", scoreColName = "score",
                                 geneColName = "GeneID", seqColName="siRNA_seq", spAvgColName = NULL)

Arguments

screen	data frame containing the results of the siRNA experiment.
seedColName	name of the column that contains the seed of the sequence (character vector)
scoreColName	name of the column that contains the score of the screen (character vector)
geneColName	name of the column that contains the names of the genes in the screen (character vector)
seqColName	name of the column that contains the names of the sequences in the screen
spAvgColName	name of the column that contains the names of the genes in the screen (character vector)

Value

input data frame after having performed the median of the replicates

Author(s)

Andrea Franceschini

Examples

	data(uuk_screen)
	mr <- median_replicates(uuk_screen)

scsR documentation built on April 28, 2020, 7:11 p.m.