SpikeLI is a package that performs the analysis of the Affymetrix spike-in data using the Langmuir Isotherm. The aim of this package is to show the advantages of a physical-chemistry based analysis of the Affymetrix microarray data compared to the traditional methods. The spike-in (or Latin square) data for the HGU95 and HGU133 chipsets have been downloaded from the Affymetrix web site. The model used in the spikeLI package is described in details in E. Carlon and T. Heim, Physica A 362, 433 (2006).
|Author||Delphine Baillon, Paul Leclercq <email@example.com>, Sarah Ternisien, Thomas Heim, Enrico Carlon <firstname.lastname@example.org>|
|Date of publication||None|
|Maintainer||Enrico Carlon <email@example.com>|
collapse: Data collapse of all concentrations into a single graph
conc133: Concentration 95
conc95: Concentration 95
hgu: Selected Probe Set data
Ivsc: Plot of intensity vs. concentration for given probes
IvsDG: Plot Intensity as function of the affinity for a given probe...
SPIKE_IN: Spike-in Probe-Set Names
SPIKE_IN95: set of spike-in genes contained in the HGU95 dataset
SPIKE_INA: Artificial Spike-in probesets
SPIKE_INB: Bacteria Spike-in probeset names
SPIKE_INH: Human Spike-in probe-set names
spikeLI.package: Analysis of Affymetrix spike-in data (HGU95 and HGU133 Latin...