Ivsc: Plot of intensity vs. concentration for given probes

In spikeLI: Affymetrix Spike-in Langmuir Isotherm Data Analysis Tool

Description

The function Ivsc plots intensity as a function of a concentration for a given probe in the spike-in Latin square experiments. It also peforms a non-linear data fit (using the package nls in the R-package stats) of the experimental data using the Langmuir Isotherm: I = I0 + Ac/(K+c) Solid and dashed lines are best fits according to this formula. Imax in the plot are given by Imax=I0+A, ie the asymptotic intensity in the limit of c to infinity.

Usage

Ivsc(probe_set, probe = "NULL", outfile = "NULL")

Arguments

probe_set	Probe set number of the probe set analyzed
probe	Integer giving the probe number (if not give the probe 1 is selected)
outfile	output the plotted data to a postscript file

Warning

Some probes have an irregular behavior and the non-linear square fit does not converge.

Author(s)

Delphine Baillon, Paul Leclercq, Sarah Ternisien, Thomas Heim and Enrico Carlon

Maintainer: Enrico Carlon <[e-mail]>

References

E. Carlon and T. Heim, Physica A 362, 433 (2006).

See Also

collapse, IvsDG, hgu, SPIKE_IN, SPIKE_INA, SPIKE_INB, SPIKE_INH

Examples

     Ivsc("37777_at",4)

spikeLI documentation built on Nov. 8, 2020, 5:54 p.m.