hodges: Hodges-Lehmann estimation for a variable of a 2x2 study

In BE: Bioequivalence Study Data Analysis

Hodges-Lehmann estimation for a variable of a 2x2 study

Description

It performs Hodges-Lehmann estimation for 2x2 study. This is usually for Tmax variable.

Usage

hodges(bedata, Var)

Arguments

bedata	Data table name. This should have at least the following columns and a variable column to be tested. GRP : Group or Sequence, 'RT' or 'TR' PRD : Period, 1 or 2 SUBJ : Subject ID TRT : Treatment or Drug, 'R' or 'T'
Var	Variable to be estimated. This should be one of the column names in bedata table. Usually 'Tmax'

Details

It nonparametrically tests Var variable equivalency from a 2x2 study. This is done for a variable which we cannot assume log-normal distribution.

Value

Wilcoxon Signed-Rank Test	A kind of nonparametric test
Hodges-Lehmann Estimate	90% confidence interval in the original scale and the percent scale

Author(s)

Kyun-Seop Bae <[e-mail]>

Examples

hodges(NCAResult4BE, "Tmax") 

BE documentation built on Jan. 7, 2023, 1:11 a.m.