powcv | R Documentation |
It calculates power for the bioequivalence test on ratio using coefficient of variation (CV).
powcv(n, CV, DesignNo = 1, True.R = 1, Alpha = 0.1, ThetaL = 0.8, ThetaU = 1.25)
n |
Sample size, n per group |
CV |
Coefficient of Variation (%) |
DesignNo |
Crossover design number. Design Number (treatment x sequence x period) 1 2x2x2 : RT TR 2 2x4x2 (Balaam Design) : TT RR RT TR 3 2x2x3 (Two-sequence Dual Design): TRR RTT 4 2x2x4 : TRRT RTTR 5 2x4x4 : TTRR RRTT TRRT RTTR 6 3x6x3 (William Design for 3 treatments) + carry-over effect : RBA ARB BAR ABR BRA RAB 7 3x6x3 (William Design for 3 treatments) - carry-over effect : RBA ARB BAR ABR BRA RAB 8 4x4x4 (William Design for 4 treatments) + carry-over effect : RCAB ARBC BACR CBRA 9 4x4x4 (William Design for 4 treatments) - carry-over effect : RCAB ARBC BACR CBRA |
True.R |
True ratio of test/reference |
Alpha |
Alpha error level |
ThetaL |
Lower limit of equivalence criteria |
ThetaU |
Upper limit of equivalence criteria |
It calculates power of sample size (n per group) with CV
.
Returns power [0, 1)
Kyun-Seop Bae <k@acr.kr>
powcv(12, 25)
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