BisqueRNA: Decomposition of Bulk Expression with Single-Cell Sequencing

Provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples. For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.

Package details

AuthorBrandon Jew [aut, cre], Marcus Alvarez [aut]
MaintainerBrandon Jew <[email protected]>
LicenseGPL-3
Version1.0.1
URL https://www.biorxiv.org/content/10.1101/669911v1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("BisqueRNA")

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BisqueRNA documentation built on Dec. 16, 2019, 1:33 a.m.