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BisqueRNA: Decomposition of Bulk Expression with Single-Cell Sequencing
Provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples. For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.
Getting started
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Package details |
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| Author | Brandon Jew [aut, cre], Marcus Alvarez [aut] |
| Maintainer | Brandon Jew <brandon.jew@ucla.edu> |
| License | GPL-3 |
| Version | 1.0.5 |
| URL | https://www.biorxiv.org/content/10.1101/669911v1 |
| Package repository | View on CRAN |
| Installation |
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