Provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples. For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.
|Author||Brandon Jew [aut, cre], Marcus Alvarez [aut]|
|Maintainer||Brandon Jew <[email protected]>|
|Package repository||View on CRAN|
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