SimulateData: Simulate data for decomposition illustration

In BisqueRNA: Decomposition of Bulk Expression with Single-Cell Sequencing

Description

Simulates bulk and single-cell expression, as well as marker genes and true proportions that can be used as an example of decomposition

Usage

SimulateData(n.ind, n.genes, n.cells, cell.types, avg.props)

Arguments

n.ind	Integer. Number of individuals to simulate
n.genes	Integer. Number of genes to simulate
n.cells	Integer. Number of cells per individual for single-cell data
cell.types	Character vector. List of cell types to simulate
avg.props	Numeric vector. List of average proportions for given cell types. Should be same length as cell.types and sum to 1

Value

A list with simulated single-cell in slot 'sc.eset' and bulk in 'bulk.eset', as well as true proportions in 'props' and marker genes in 'markers'.

Examples

library(Biobase)
sim.data <- SimulateData(n.ind=10, n.genes=100, n.cells=100,
                         cell.types=c("Neurons", "Astrocytes", "Microglia"),
                         avg.props=c(.5, .3, .2))

BisqueRNA documentation built on May 24, 2021, 1:06 a.m.