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Routines for performing empirical calibration of observational study estimates. By using a set of negative control hypotheses we can estimate the empirical null distribution of a particular observational study setup. This empirical null distribution can be used to compute a calibrated pvalue, which reflects the probability of observing an estimated effect size when the null hypothesis is true taking both random and systematic error into account.
Package details 


Author  Martijn Schuemie, Marc Suchard 
Date of publication  20171107 16:33:45 UTC 
Maintainer  Martijn Schuemie <[email protected]> 
License  Apache License 2.0 
Version  1.3.6 
URL  https://github.com/OHDSI/EmpiricalCalibration 
Package repository  View on CRAN 
Installation 
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