View source: R/EmpiricalCalibrationUsingAsymptotics.R
fitNullNonNormalLl | R Documentation |
fitNullNonNormalLl
fits the null distribution to a set of negative controls
fitNullNonNormalLl(likelihoodApproximations)
likelihoodApproximations |
Either a data frame containing normal, skew-normal, or custom parametric likelihood approximations, or a list of (adaptive) grid likelihood profiles. |
This function fits a Gaussian function to the negative control estimates, using non-normal approximations of the per-negative control log likelihood.
An object containing the parameters of the null distribution.
data(sccs) negatives <- sccs[sccs$groundTruth == 0, ] null <- fitNullNonNormalLl(negatives) null
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