View source: R/LlrCalibration.R
calibrateLlr | R Documentation |
calibrateLlr
computes calibrated log likelihood ratio using the fitted null distribution
calibrateLlr(null, likelihoodApproximation, twoSided = FALSE, upper = TRUE)
null |
An object of class |
likelihoodApproximation |
Either a data frame containing normal, skew-normal, or custom parametric likelihood approximations, or a list of (adaptive) grid likelihood profiles. |
twoSided |
Compute two-sided (TRUE) or one-sided (FALSE) p-value? |
upper |
If one-sided: compute p-value for upper (TRUE) or lower (FALSE) bound? |
The calibrated log likelihood ratio.
data(sccs)
negatives <- sccs[sccs$groundTruth == 0, ]
null <- fitNull(negatives$logRr, negatives$seLogRr)
positive <- sccs[sccs$groundTruth == 1, ]
calibrateLlr(null, positive)
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