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Hapi: Inference of Chromosome-Length Haplotypes Using Genomic Data of Single Gamete Cells
Inference of chromosome-length haplotypes using a few haploid gametes of an individual. The gamete genotype data may be generated from various platforms including genotyping arrays and sequencing even with low-coverage. Hapi simply takes genotype data of known hetSNPs in single gamete cells as input and report the high-resolution haplotypes as well as confidence of each phased hetSNPs. The package also includes a module allowing downstream analyses and visualization of identified crossovers in the gametes.
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Package details |
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| Author | Ruidong Li, Han Qu, Jinfeng Chen, Shibo Wang, Le Zhang, Julong Wei, Sergio Pietro Ferrante, Mikeal L. Roose, Zhenyu Jia |
| Bioconductor views | Genetics GenomicVariation HiddenMarkovModel Microarray SNP Sequencing SingleCell |
| Maintainer | Ruidong Li <rli012@ucr.edu> |
| License | GPL-3 |
| Version | 0.0.3 |
| Package repository | View on CRAN |
| Installation |
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