Description Usage Arguments Value See Also Examples
provides concordance probabilities of relative pairs for a causal model with G*E component
1 | drgen(fd,fr,e)
|
fd |
an array (size=number of dominant genes+recessive genes) of dominant gene frequencies including 0 values of recessive genes of G component of G*E interacting with E of G*E |
fr |
an array (size=number of dominant genes+recessive genes) of recessive gene frequencies including 0 values of dominant genes of G component of G*E interacting with E of G*E |
e |
a proportion of population who are exposed to environmental cause of G*E interacting with genetic cause of G*E during their entire life |
a list of the g*e proportion in population and a matrix of NN, ND, and DD probabilities of 9 relative pairs: 1:mzt,2:parent-offspring,3:dzt,4:sibling,5:2-direct(grandparent-grandchild),6:3rd(uncle-niece),7:3-direct(great-grandparent-great-grandchild),8:4th (causin),9:4d(great-great-grandparent-great-great-grandchild)
drgene.gm
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 | ### PLI=0.01.
ppt<-0.01
### g*e model
pge<-ppt # the proportion of G*E component in total populations
ppe<-0.5
ppg<-pge/ppe
fd<-0.0005 # one dominant gene
tt<-3 # the number of recessive genes
temp<-sqrt(1-((1-ppg)/(1-fd)^2)^(1/tt))
fr<-c(array(0,length(fd)),array(temp,tt))
fd<-c(fd,array(0,tt))
drgen(fd,fr,ppe)
|
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.