DiffGenesSelection: Differential expression for a selection of objects

Description Usage Arguments

Description

Internal function of DiffGenes.

Usage

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DiffGenesSelection(List, Selection, geneExpr = NULL, nrclusters = NULL,
  method = "limma", sign = 0.05, topG = NULL, fusionsLog = TRUE,
  weightclust = TRUE, names = NULL)

Arguments

List

A list of the clustering outputs to be compared. The first element of the list will be used as the reference in ReorderToReference.

Selection

If differential gene expression should be investigated for a specific selection of objects, this selection can be provided here. Selection can be of the type "character" (names of the objects) or "numeric" (the number of specific cluster). Default is NULL.

geneExpr

The gene expression matrix or ExpressionSet of the objects. The rows should correspond with the genes.

nrclusters

Optional. The number of clusters to cut the dendrogram in. The number of clusters should not be specified if the interest lies only in a specific selection of objects which is known by name. Otherwise, it is required. Default is NULL.

method

The method to applied to look for DE genes. For now, only the limma method is available. Default is "limma".

sign

The significance level to be handled. Default is 0.05.

topG

Overrules sign. The number of top genes to be shown. Default is NULL.

fusionsLog

Logical. To be handed to ReorderToReference: indicator for the fusion of clusters. Default is TRUE

weightclust

Logical. To be handed to ReorderToReference: to be used for the outputs of CEC, WeightedClust or WeightedSimClust. If TRUE, only the result of the Clust element is considered. Default is TRUE.

names

Optional. Names of the methods. Default is NULL.


IntClust documentation built on May 2, 2019, 5:51 a.m.