Description Usage Arguments Details Value Author(s) Examples
Summarizes module hub/hierarchy/membership into a data.frame table format.
1 2 | module_convert_to_table(MEGENA.output,mod.pval = 0.05,
hub.pval = 0.05,min.size = 10,max.size)
|
MEGENA.output |
A list object. The output from "do.MEGENA()". |
mod.pval |
module compactness significance p-value, to identify modules with significant compactness. |
hub.pval |
node degree significance p-value to identify nodes with significantly high degree. |
min.size |
minimum module size allowed to finalize in the summary output. |
max.size |
maximum module size allowed to finalize in the summary output. |
the resulting data.frame contains the following essential columns: id, module.parent and module. If the co-expression network bears significant hubs, it will additionally have node.degree (connectivity), node.strength (sum of edge weights) and is.hub column to supplement hub information.
A data.frame with the columns:
id |
gene name |
module.parent |
parent module id |
module |
module name. |
Won-Min Song
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 | ## Not run:
rm(list = ls())
data(Sample_Expression)
ijw <- calculate.correlation(datExpr[1:100,],doPerm = 2)
el <- calculate.PFN(ijw[,1:3])
g <- graph.data.frame(el,directed = FALSE)
MEGENA.output <- do.MEGENA(g = g,remove.unsig = FALSE,doPar = FALSE,n.perm = 10)
output.summary <- MEGENA.ModuleSummary(MEGENA.output,
mod.pvalue = 0.05,hub.pvalue = 0.05,
min.size = 10,max.size = 5000,
annot.table = NULL,id.col = NULL,symbol.col = NULL,
output.sig = TRUE)
module.df = module_convert_to_table(MEGENA.output,mod.pval = 0.05,
hub.pval = 0.05,min.size = 10,max.size)
head(module.df)
## End(Not run)
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