Description Usage Arguments Author(s)
Provide a simulation function using ms software. If you have no ms and no Linux, you can not run this function.
1 2 3 4 5 6 | MOJOV.simulation(cohortSize = 500, nReps = 2, theta = 10, sites = NULL,
affectNum = NULL, MAF = 0.01, totalMAF = 0.05, lambda = 1, sd = NULL,
type = c("alpha","belta"), sampleNum = 100, outFile = NULL, plot = FALSE,
codeMethod = c("Proportion", "Indicator", "ChuanhuaXin"),
weightMethod = c("ChuanhuaXin"), testMethod = c("FTest", "WaldTest",
"LRT", "Sandwich", "all"), save = NULL)
|
cohortSize |
Specify the size for analysis cohort. |
nReps |
Specify the number of independent samples to generate. |
theta |
Specify the mutation parameter,see details. |
sites |
Specify the number of sites, it is optional. |
affectNum |
Specify the number or ratio for affect sites.If it is less than 1, it will be the ratio of affect rare variants sites to all rare variants. |
MAF |
Specify the minor allele frequency, and the default value is 0.01. |
totalMAF |
Specify the total minor allele frequency for affect variants. And the default value is 0.05. |
lambda |
Specify the lambda for phenotype standard error.See details. |
sd |
Specify the standard error.See details. |
type |
It can be "alpha" and "belta". The default value is "alpha". |
sampleNum |
Specify the number of sample. The default value is 100. |
outFile |
You can specify a file name to save your data from ms. |
plot |
You can set it as TRUE, it will plot the result using lattice package. |
codeMethod |
See MOJOV.analysis |
weightMethod |
See MOJOV.analysis |
testMethod |
See MOJOV.analysis |
save |
You can specify a file name to save your simulation result. |
Ke-Hao Wu
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