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Phase12Compare: Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes
Simulating and conducting four phase 12 clinical trials with correlated binary bivariate outcomes described. Uses the 'Efftox' (efficacy and toxicity tradeoff, <https://biostatistics.mdanderson.org/SoftwareDownload/SingleSoftware/Index/2>) and SPSO (Semi-Parametric Stochastic Ordering) models with Utility and Desirability based objective functions for dose finding.
Getting started
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Package details |
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| Author | Andrew G Chapple |
| Maintainer | Andrew G Chapple <achapp@lsuhsc.edu> |
| License | GPL-2 |
| Version | 1.5 |
| Package repository | View on CRAN |
| Installation |
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