Phase12Compare: Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes

Simulating and conducting four phase 12 clinical trials with correlated binary bivariate outcomes described. Uses the 'Efftox' (efficacy and toxicity tradeoff, <>) and SPSO (Semi-Parametric Stochastic Ordering) models with Utility and Desirability based objective functions for dose finding.

Getting started

Package details

AuthorAndrew G Chapple
MaintainerAndrew G Chapple <>
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:

Try the Phase12Compare package in your browser

Any scripts or data that you put into this service are public.

Phase12Compare documentation built on July 31, 2020, 5:07 p.m.