Description Usage Arguments Value
This function returns the optimal acceptable dose number to assign the next patient cohort or stops the trial if no dose is deemed acceptable.
1 2 3 4 5 6 7 8 9 10 11 12 13 | AssignEffToxUT(
YE,
YT,
Doses,
Dose,
DosesTried,
Hypermeans,
Hypervars,
UT,
PiLim,
ProbLim,
B
)
|
YE |
Vector containing observed efficacy indicators. |
YT |
Vector containing observed toxicity indicators. |
Doses |
Vector containing numbered Doses of patients in trial. |
Dose |
Vector containing the standardized doses considered. |
DosesTried |
Binary vector corresponding to which doses have been tried. |
Hypermeans |
Vector containing prior hypermeans of length 6 for Eff-Tox parameters. |
Hypervars |
Vector containing prior hypervariances of length 6 for Eff-Tox parameters. |
UT |
2x2 utility matrix. |
PiLim |
Vector of length two with PiLim[1] containing the acceptable lower limit on efficacy probability and PiLim[2] containing the acceptable upper limit on toxicity probability. |
ProbLim |
Vector of length two with ProbLim[1] containing the probability cutoff for acceptable efficacy probability and ProbLim[2] containing the probability cutoff for acceptable toxicity probability. |
B |
Number of iterations to perform in the MCMC. |
The optimal dose level to administer the next patient cohort.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.