Description Usage Arguments Value Examples
Takes arguments of data, hypermens and hypervariance vectors and returns a list of posterior samples from the Utility based phase12 model decribed by Chapple and Thall (2019).
1 | UTEFFTOX(YE, YT, Doses, HypermeansEFF, HypermeansTOX, Hypervars, B)
|
YE |
Binary indicator vector of efficacy status. |
YT |
Binary indicator vector of toxicity status. |
Doses |
Vector of integer Doses given to patients. |
HypermeansEFF |
Vector of length nDose for dose prior means for efficacy. |
HypermeansTOX |
Vector of length nDose for dose prior means for toxicity |
Hypervars |
Length 3 vector of hypervariances.Hypervars(1) contains sigma_0^2, Hypervars(2) contains sigma_mu, Hypervars(3) contains tau - the frailty variance. |
B |
Number of iterations to run for the MCMC. |
A list of posterior samples after burnin in order: Posterior efficacy dose-vector, Posterior toxicity dose-vector, Posterior correlation.
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