PivotTransformData: "PivotTransformation"

In REIDS: Random Effects for the Identification of Differential Splicing

Description

The PivotTransformation function converts a data frame with multiple rows per gene into a .csv file with one row per gene. This is the first step in data transformation to apply the REIDS function on a HPC Cluster.

Usage

PivotTransformData(Data, GeneID = NULL, ExonID = NULL,
  REMAPSplitFile = NULL, NotAnnotated = FALSE, Location = NULL,
  Name = "Pivot")

Arguments

Data	The data frame to be transformed.
GeneID	A character vector of the the gene IDs that correspond to the rows of the data frame. Necessary if no GeneID column is present in the data frame
ExonID	A character vector of the the gene IDs that correspond to the rows of the data frame. Necessary if no ExonID column is present in the data frame
REMAPSplitFile	The name of the file with the REMAP information regarding the split of the probe sets if the TC ID is annotated to mutiple genes.
NotAnnotated	Logical. Should the probe sets which are not annotated to a gene still be included? If FALSE, these are excluded. If TRUE, these are included. Default is FALSE.
Location	The location where the file should be saved. If NULL, the object is returned to the user. Otherwise, a file with the specified name is created.
Name	The name of the output file. Defaults to "Pivot".

Details

All information concerning one gene is gathered. The first column of the returned data frame is the gene ID, the second column contains the exon IDs of all exons of that gene. The third colum indicates the number of probes per exon, the fourth contains the values of thos probes per sample and the last column contains the sample names.This way a .csv file is created for processing on a HPC cluster.

Value

A data frame with one row per gene. This row contains the values for each exon per sample and is convenient for processing on a HPC cluster. Futher also a data frame with a column of the gene ID's is returned.

Examples

data(TC12000010)

PivotTest=PivotTransformData(Data=TC12000010,GeneID=NULL,ExonID=NULL,
Location=NULL)

## Not run: 
data(TC1500264)

PivotTransformData(Data=TC1500264,GeneID=NULL,ExonID=NULL,
REMAPSplitFile="TC1500264_Gene_SplitFile.txt",Location=
"Output",Name="TC1500264_Pivot")

## End(Not run)

REIDS documentation built on May 2, 2019, 6:42 a.m.