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SeqKat: Detection of Kataegis
Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 <doi:10.1101/287839>.
Package details |
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| Author | Fouad Yousif [aut], Xihui Lin [aut], Fan Fan [aut], Christopher Lalansingh [aut], John Macdonald [aut], Paul C. Boutros [cre] |
| Maintainer | Paul C. Boutros <pboutros@sbpdiscovery.org> |
| License | GPL (>= 2) |
| Version | 0.0.9 |
| URL | https://github.com/TheBoutrosLab/package-SeqKat |
| Package repository | View on CRAN |
| Installation |
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