abic_alcoholic_hepatitis: ABIC Score for Alcoholic Hepatitis

In cliot: Clinical Indices and Outcomes Tools

ABIC Score for Alcoholic Hepatitis

Description

Calculates the ABIC (Age, Bilirubin, INR, Creatinine) Score to stratify the risk of death at 90 days in patients with alcoholic hepatitis. It categorizes patients into Low, Intermediate, and High risk groups, helping to guide treatment decisions such as the use of corticosteroids.

Usage

abic_alcoholic_hepatitis(age, bilirubin, inr, creatinine,
                         bilirubin_units = "mg/dL", creatinine_units = "mg/dL")

Arguments

age	Numeric. Patient age in years.
bilirubin	Numeric. Serum bilirubin level.
inr	Numeric. International Normalized Ratio.
creatinine	Numeric. Serum creatinine level.
bilirubin_units	String. Units for bilirubin. Options: "mg/dL" (default) or "umol/L".
creatinine_units	String. Units for creatinine. Options: "mg/dL" (default) or "umol/L".

Value

A list containing:

ABIC_Score	The calculated score.
Risk_Group	Risk classification (Low, Intermediate, High).
Est_90_Day_Survival	Estimated survival rate at 90 days based on the validation cohort.

References

Dominguez M, Rincon D, Abraldes JG, et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol. 2008;103(11):2747-2756. doi:10.1111/j.1572-0241.2008.02104.x

Examples

# Example 1: High Risk
# 50yo, Bili 15 mg/dL, INR 2.0, Cr 1.5 mg/dL
# Score = (50*0.1) + (15*0.08) + (1.5*0.3) + (2.0*0.8) = 5 + 1.2 + 0.45 + 1.6 = 8.25 (Intermediate)
abic_alcoholic_hepatitis(50, 15, 2.0, 1.5)

# Example 2: Low Risk
# 40yo, Bili 3 mg/dL, INR 1.1, Cr 0.8 mg/dL
abic_alcoholic_hepatitis(40, 3, 1.1, 0.8)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.