akin_aki_staging: AKIN Classification for Acute Kidney Injury (AKI)

In cliot: Clinical Indices and Outcomes Tools

AKIN Classification for Acute Kidney Injury (AKI)

Description

Classifies the severity of Acute Kidney Injury (AKI) based on the Acute Kidney Injury Network (AKIN) criteria. The staging is determined by the worst of two criteria: serum creatinine changes (relative to baseline) or urine output duration.

Usage

akin_aki_staging(baseline_creatinine, max_creatinine,
                 urine_output_stage = 0, rrt_initiated = 0)

Arguments

baseline_creatinine	Numeric. Baseline serum creatinine in mg/dL.
max_creatinine	Numeric. Maximum serum creatinine reached within 48 hours.
urine_output_stage	Numeric (0, 1, 2, or 3). The stage corresponding to the patient's urine output criteria. 0: Normal (> 0.5 ml/kg/hr). 1: < 0.5 ml/kg/hr for > 6 hours. 2: < 0.5 ml/kg/hr for > 12 hours. 3: < 0.3 ml/kg/hr for 24 hours OR Anuria for 12 hours.
rrt_initiated	Numeric (0 or 1). Was Renal Replacement Therapy (RRT) initiated? (1 = Yes, automatically Stage 3).

Value

A list containing:

AKIN_Stage	The final classification (No AKI, Stage 1, Stage 2, or Stage 3).
Numeric_Stage	Integer representation of the stage (0-3).
Criteria_Met	Breakdown of stages derived from Creatinine vs. Urine Output components.

References

Mehta RL, Kellum JA, Shah SV, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31. doi:10.1186/cc5713

Examples

# Example 1: Stage 1 (Creatinine rise >= 0.3 mg/dL)
# Base 1.0, Max 1.3, Normal UO
akin_aki_staging(1.0, 1.3, 0, 0)

# Example 2: Stage 3 (Urine Output criteria)
# Base 1.0, Max 1.2 (No AKI by Cr), UO < 0.3 for 24h (Stage 3)
akin_aki_staging(1.0, 1.2, 3, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.