antivenom_dosing_algorithm: Antivenom Dosing Algorithm (CroFab)

In cliot: Clinical Indices and Outcomes Tools

Antivenom Dosing Algorithm (CroFab)

Description

Determines the recommended dosing for CroFab antivenom in patients with North American Crotalid (pit viper) envenomation. The algorithm guides the initial dose to achieve control of symptoms (arrest of local progression, normalization of coagulopathy, and resolution of systemic signs) and subsequent maintenance therapy.

Usage

antivenom_dosing_algorithm(signs_of_envenomation, initial_control_achieved = FALSE)

Arguments

signs_of_envenomation	Numeric (0 or 1). Presence of signs of envenomation (swelling, tenderness, ecchymosis, coagulopathy, or systemic signs). (1 = Yes, 0 = No).
initial_control_achieved	Numeric (0 or 1). Has initial control been achieved? defined as the arrest of local progression, improvement in systemic signs, and stabilization of coagulation labs. (1 = Yes, 0 = No).

Value

A list containing:

Recommendation	Guidance on initial or repeat dosing.
Maintenance_Therapy	Instructions for maintenance doses if control is achieved.

References

Lavonas EJ, Ruha AM, Banner W, et al. Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop. BMC Emerg Med. 2011;11:2. doi:10.1186/1471-227X-11-2

Examples

# Example 1: Initial Presentation
# Patient with swelling and pain
antivenom_dosing_algorithm(1, 0)

# Example 2: Control Achieved
# Patient received initial dose, swelling stopped, labs stable
antivenom_dosing_algorithm(1, 1)

# Example 3: Dry Bite
# No signs of envenomation
antivenom_dosing_algorithm(0, 0)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.