absolute_neutrophil_count: Absolute Neutrophil Count (ANC)

In cliot: Clinical Indices and Outcomes Tools

Absolute Neutrophil Count (ANC)

Description

Calculates the Absolute Neutrophil Count (ANC), a measure of the number of neutrophil granulocytes (including segmented neutrophils and bands) present in the blood. ANC is critical for assessing the risk of infection in patients undergoing chemotherapy or those with other immune system suppressions.

Usage

absolute_neutrophil_count(wbc, neutrophils_percent, bands_percent = 0)

Arguments

wbc	Numeric. The total White Blood Cell count. Can be entered as cells/microL (e.g., 4500) or k/microL (e.g., 4.5).
neutrophils_percent	Numeric. The percentage of segmented neutrophils ("segs" or "polys") from the differential (0-100).
bands_percent	Numeric (Optional). The percentage of band neutrophils ("bands") from the differential (0-100). Defaults to 0 if not reported.

Value

A list containing:

ANC	The calculated Absolute Neutrophil Count. The unit scale matches the WBC input (e.g., if WBC is in k/uL, ANC is in k/uL).
Interpretation	Risk classification (Normal, Mild, Moderate, or Severe Neutropenia). The function attempts to auto-detect the unit scale for interpretation.

References

Al-Gwaiz LA, Babay HH. The diagnostic value of absolute lymphocyte count in typhoid fever. J Infect Dev Ctries. 2007;1(3):260-265. (General hematology reference).

Examples

# Example 1: Severe Neutropenia (Chemotherapy patient)
# WBC 1.2 k/uL, 20% Segs, 5% Bands
# ANC = 1.2 * (0.20 + 0.05) = 0.3 k/uL (300 cells/uL)
absolute_neutrophil_count(1.2, 20, 5)

# Example 2: Normal
# WBC 6000 cells/uL, 50% Segs, 0% Bands
absolute_neutrophil_count(6000, 50)

cliot documentation built on Dec. 1, 2025, 1:06 a.m.