cubar: Codon Usage Bias Analysis

A suite of functions for rapid and flexible analysis of codon usage bias. It provides in-depth analysis at the codon level, including relative synonymous codon usage (RSCU), tRNA weight calculations, machine learning predictions for optimal or preferred codons, and visualization of codon-anticodon pairing. Additionally, it can calculate various gene- specific codon indices such as codon adaptation index (CAI), effective number of codons (ENC), fraction of optimal codons (Fop), tRNA adaptation index (tAI), mean codon stabilization coefficients (CSCg), and GC contents (GC/GC3s/GC4d). It also supports both standard and non-standard genetic code tables found in NCBI, as well as custom genetic code tables.

Package details

AuthorHong Zhang [aut, cre] (<https://orcid.org/0000-0002-4064-9432>), Mengyue Liu [aut], Bu Zi [aut]
MaintainerHong Zhang <mt1022.dev@gmail.com>
LicenseMIT + file LICENSE
Version1.1.0
URL https://github.com/mt1022/cubar https://mt1022.github.io/cubar/
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("cubar")

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cubar documentation built on April 3, 2025, 8:58 p.m.