median_prob_tox: Median toxicity rate at each dose.

In escalation: Modular Approach to Dose Finding Clinical Trials

Median toxicity rate at each dose.

Description

Get the estimated median toxicity rate at each dose under investigation. This is a set of modelled statistics. The underlying models estimate toxicity probabilities in different ways. If no model-based estimate of the median is available, this function will return a vector of NAs.

Usage

median_prob_tox(x, ...)

Arguments

x	Object of class selector
...	arguments passed to other methods

Value

a numerical vector

Examples

# CRM example
skeleton <- c(0.05, 0.1, 0.25, 0.4, 0.6)
target <- 0.25
outcomes <- '1NNN 2NTN'
fit <- get_dfcrm(skeleton = skeleton, target = target) %>% fit(outcomes)
fit %>% median_prob_tox()

escalation documentation built on May 31, 2023, 6:32 p.m.