prob_tox_quantile: Quantile of the toxicity rate at each dose.

In escalation: Modular Approach to Dose Finding Clinical Trials

Quantile of the toxicity rate at each dose.

Description

Get the estimated quantile of the toxicity rate at each dose under investigation. This is a set of modelled statistics. The underlying models estimate toxicity probabilities in different ways. If no model-based estimate of the median is available, this function will return a vector of NAs.

Usage

prob_tox_quantile(x, p, ...)

Arguments

x	Object of class selector
p	quantile probability, decimal value between 0 and 1
...	arguments passed to other methods

Value

a numerical vector

Examples

# CRM example
skeleton <- c(0.05, 0.1, 0.25, 0.4, 0.6)
target <- 0.25
outcomes <- '1NNN 2NTN'
fit <- get_dfcrm(skeleton = skeleton, target = target) %>% fit(outcomes)
fit %>% prob_tox_quantile(p = 0.9)

escalation documentation built on May 31, 2023, 6:32 p.m.