Flexible parametric models for time-to-event data, including the Royston-Parmar spline model, generalized gamma and generalized F distributions. Any user-defined parametric distribution can be fitted, given at least an R function defining the probability density or hazard. There are also tools for fitting and predicting from fully parametric multi-state models.

Author | Christopher Jackson <chris.jackson@mrc-bsu.cam.ac.uk> |

Date of publication | 2016-05-11 12:06:27 |

Maintainer | Christopher Jackson <chris.jackson@mrc-bsu.cam.ac.uk> |

License | GPL (>= 2) |

Version | 1.0.0 |

https://github.com/chjackson/flexsurv-dev |

**basis:** Natural cubic spline basis

**bc:** Breast cancer survival data

**bos:** Bronchiolitis obliterans syndrome after lung transplants

**flexsurv-package:** flexsurv: Flexible parametric survival and multi-state models

**flexsurvreg:** Flexible parametric regression for time-to-event data

**flexsurvspline:** Flexible survival regression using the Royston/Parmar spline...

**GenF:** Generalized F distribution

**GenF.orig:** Generalized F distribution (original parameterisation)

**GenGamma:** Generalized gamma distribution

**GenGamma.orig:** Generalized gamma distribution (original parameterisation)

**Gompertz:** The Gompertz distribution

**hazard:** Hazard and cumulative hazard functions

**lines.flexsurvreg:** Add fitted flexible survival curves to a plot

**Llogis:** The log-logistic distribution

**model.frame.flexsurvreg:** Extract original data from 'flexsurvreg' objects.

**msfit.flexsurvreg:** Cumulative intensity function for parametric multi-state...

**normboot.flexsurvreg:** Simulate from the asymptotic normal distribution of parameter...

**pars.fmsm:** Transition-specific parameters in a flexible parametric...

**plot.flexsurvreg:** Plots of fitted flexible survival models

**pmatrix.fs:** Transition probability matrix from a fully-parametric,...

**pmatrix.simfs:** Transition probability matrix from a fully-parametric,...

**qgeneric:** Generic function to find quantiles of a distribution

**sim.fmsm:** Simulate paths through a fully parametric semi-Markov...

**summary.flexsurvreg:** Summaries of fitted flexible survival models

**Survspline:** Royston/Parmar spline survival distribution

**totlos.fs:** Total length of stay in particular states for a...

**totlos.simfs:** Expected total length of stay in specific states, from a...

**unroll.function:** Convert a function with matrix arguments to a function with...

**WeibullPH:** Weibull distribution in proportional hazards parameterisation

flexsurv

flexsurv/inst

flexsurv/inst/CITATION

flexsurv/inst/NEWS

flexsurv/inst/doc

flexsurv/inst/doc/flexsurv-examples.pdf

flexsurv/inst/doc/flexsurv.R

flexsurv/inst/doc/flexsurv-examples.R

flexsurv/inst/doc/flexsurv.pdf

flexsurv/tests

flexsurv/tests/test_base.R

flexsurv/tests/testthat

flexsurv/tests/testthat/test_utils.R

flexsurv/tests/testthat/test_outputs.R

flexsurv/tests/testthat/test_flexsurvreg.R

flexsurv/tests/testthat/test_custom.R

flexsurv/tests/testthat/test_spline.R

flexsurv/tests/testthat/test_deriv.R

flexsurv/tests/testthat/test_mstate.R

flexsurv/NAMESPACE

flexsurv/data

flexsurv/data/bc.rda

flexsurv/data/bc.txt.gz

flexsurv/data/bosms3.rda

flexsurv/data/bosms4.rda

flexsurv/Changelog

flexsurv/R

flexsurv/R/Llogis.R
flexsurv/R/utils.R
flexsurv/R/mstate.R
flexsurv/R/Gompertz.R
flexsurv/R/custom.R
flexsurv/R/flexsurvreg.R
flexsurv/R/spline.R
flexsurv/R/fracpoly.R
flexsurv/R/GenGamma.R
flexsurv/R/deriv.R
flexsurv/R/GenF.R
flexsurv/vignettes

flexsurv/vignettes/flexsurv.bib

flexsurv/vignettes/bosmsm.pdf

flexsurv/vignettes/flexsurv-examples.Rnw

flexsurv/vignettes/flexsurv.Rnw

flexsurv/MD5

flexsurv/build

flexsurv/build/vignette.rds

flexsurv/DESCRIPTION

flexsurv/man

flexsurv/man/totlos.fs.Rd
flexsurv/man/GenF.Rd
flexsurv/man/basis.Rd
flexsurv/man/GenGamma.orig.Rd
flexsurv/man/sim.fmsm.Rd
flexsurv/man/model.frame.flexsurvreg.Rd
flexsurv/man/Gompertz.Rd
flexsurv/man/pmatrix.simfs.Rd
flexsurv/man/pars.fmsm.Rd
flexsurv/man/flexsurvreg.Rd
flexsurv/man/summary.flexsurvreg.Rd
flexsurv/man/Llogis.Rd
flexsurv/man/totlos.simfs.Rd
flexsurv/man/flexsurvspline.Rd
flexsurv/man/plot.flexsurvreg.Rd
flexsurv/man/bc.Rd
flexsurv/man/hazard.Rd
flexsurv/man/WeibullPH.Rd
flexsurv/man/normboot.flexsurvreg.Rd
flexsurv/man/msfit.flexsurvreg.Rd
flexsurv/man/pmatrix.fs.Rd
flexsurv/man/GenGamma.Rd
flexsurv/man/flexsurv-package.Rd
flexsurv/man/bos.Rd
flexsurv/man/GenF.orig.Rd
flexsurv/man/qgeneric.Rd
flexsurv/man/Survspline.Rd
flexsurv/man/lines.flexsurvreg.Rd
flexsurv/man/unroll.function.Rd
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