observLmer2: Variance components for normal data 2

In fullfact: Full Factorial Breeding Analysis

Variance components for normal data 2

Description

Extracts additive genetic, non-additive genetic, and maternal variance components from a linear mixed-effect model using the lmer function of the lme4 package. Model random effects are dam, sire, and dam by sire. Options to include one random position and/or one random block effect(s).

Usage

observLmer2(observ, dam, sire, response, position = NULL, block = NULL, ml = F)

Arguments

observ	Data frame of observed data.
dam	Column name containing dam (female) parent identity information.
sire	Column name containing sire (male) parent identity information.
response	Column name containing the offspring (response) phenotype values.
position	Optional column name containing position factor information.
block	Optional column name containing block factor information.
ml	Default is FALSE for restricted maximum likelihood. Change to TRUE for maximum likelihood.

Details

Extracts the dam, sire, dam, dam by sire, and residual variance components. Extracts optional position and block variance components. Calculates the total variance component. Calculates the additive genetic, non-additive genetic, and maternal variance components (see Lynch and Walsh 1998, p. 603). Significance values for the random effects are determined using likelihood ratio tests (Bolker et al. 2009).

Value

A list object containing the raw variance components, the variance components as a percentage of the total variance component. Also, contains the difference in AIC and BIC, and likelihood ratio test Chi-square and p-value for all random effects.

Note

Maximum likelihood (ML) estimates the parameters that maximize the likelihood of the observed data and has the advantage of using all the data and accounting for non-independence (Lynch and Walsh 1998, p. 779; Bolker et al. 2009). On the other hand, ML has the disadvantage of assuming that all fixed effects are known without error, producing a downward bias in the estimation of the residual variance component. This bias can be large if there are lots of fixed effects, especially if sample sizes are small. Restricted maximum likelihood (REML) has the advantage of not assuming the fixed effects are known and averages over the uncertainty, so there can be less bias in the estimation of the residual variance component. However, REML only maximizes a portion of the likelihood to estimate the effect parameters, but is the preferred method for analyzing large data sets with complex structure.

References

Bolker BM, Brooks ME, Clark CJ, Geange SW, Poulsen JR, Stevens MHH, White J-SS. 2009. Generalized linear mixed models: a practical guide for ecology and evolution. Trends in Ecology and Evolution 24(3): 127-135. DOI: 10.1016/j.tree.2008.10.008

Lynch M, Walsh B. 1998. Genetics and Analysis of Quantitative Traits. Sinauer Associates, Massachusetts.

See Also

observLmer, observLmer3

Examples

data(chinook_length) #Chinook salmon offspring length
length_mod2<- observLmer2(observ=chinook_length,dam="dam",sire="sire",response="length",
position="tray")
length_mod2

fullfact documentation built on May 29, 2024, 1:21 a.m.