Man pages for gimap
Calculate Genetic Interactions for Paired CRISPR Targets

calc_giCalculate Genetic Interaction scores
check_internet_availableCheck if internet/URL is available
cn_setupDownload and set up DepMap CN
ctrl_genesDownload and set up control genes
delete_annotationRefresh the annotation files by redownloading them
delete_example_dataDelete cached Figshare example files
encrypt_creds_pathDefault creds path
example_data_folderFolder used for Figshare example data
figshare_manual_download_messageBuild manual download instructions for Figshare files
get_example_dataReturns example data for package
get_figshareHandler function for GET requests from Figshare
gimap_annotateAnnotate gimap data
gimap_data_dirResolve and create data directory
gimap_filterA function to run filtering
gimap_normalizeNormalize Log fold changes
gimap_objectMake an empty gimap dataset object
gimap_statsDo tests -an internal function used by calc_gi() function
key_encrypt_creds_pathGet file path to an key encryption RDS
normalize_depmap_metadataNormalize DepMap metadata for downstream joins
pipePipe operator
plot_crisprPlot CRISPR scores after normalization
plot_exp_v_obs_scatterExpected vs Observed CRISPR Scatterplot
plot_rank_scatterRank plot for target-level GI scores
plot_targetsTarget bar plot for CRISPR scores
plot_themeStandardized plot theme
plot_volcanoVolcano plot for GI scores
qc_cdfCreate a CDF for the pgRNA normalized counts
qc_constructs_countzero_barCreate a bar graph that shows the number of replicates with a...
qc_cor_heatmapCreate a correlation heatmap for the pgRNA CPMs
qc_filter_plasmidCreate a filter for pgRNAs which have a low log2 CPM value...
qc_filter_zerocountsFilter out samples of zero counts Create a filter for pgRNAs...
qc_plasmid_histogramCreate a histogram with plasmid log2 CPM values and ascertain...
qc_sample_histCreate a histogram for the pgRNA log2 CPMs, faceted by sample
qc_variance_histCreate a histogram for the variance within replicates for...
resolve_example_data_dirDefault directory for [get_example_data()] and related...
run_qcRun Quality Control Checks
save_example_timepoint_dataSet up example count data
save_example_treatment_dataSet up example count data
setup_dataMaking a new gimap dataset
supported_cell_linesList the supported cell lines
tpm_setupDownload and set up DepMap TPM data
gimap documentation built on July 10, 2026, 1:06 a.m.