Description Usage Arguments Details Value See Also Examples
The function fits dose response curves.
1 2 | drFitSpline(conc, test, drID = "undefined",
control = grofit.control())
|
conc |
Numeric vector, concentration (dose) data. |
test |
Numeric vector, response data beloning to |
drID |
Character, identifying the dose response data. |
control |
Object of class |
The function uses the R internal function smooth.spline
to fit a spline to the provided data. From the resulting curve the EC50 value is calculated.
Generates an object of class drFit
raw.conc |
Raw data provided to the function as |
raw.test |
Raw data provided to the function as |
drID |
Character, identifying the dose response data. |
fit.conc |
Fitted concentration values. |
fit.test |
Fitted response values. |
spline |
|
fitFlag |
Logical, indicating wether a spline could fitted successfully to data. |
reliable |
Logical, indicating wether the provided data is reliable (to be set manually). |
control |
Object of class |
parameters |
List of parameters estimated from dose response curve fit. |
EC50 |
Half maximal concentration. |
yEC50 |
Response value related to EC50. |
EC50.orig |
EC50 value in original scale, if a transformation was applied. |
xEC50.orig |
Response value for EC50 in original scale, if a transformation was applied. |
drFit
, summary.drFitSpline
, plot.drFitSpline
1 2 3 4 5 |
=== Dose response curve estimation ================
--- EC 50 -----------------------------------------
--> undefined
xEC50 14.8758758758759 yEC50 0.51559902180392
EC50 yEC50 EC50.orig yEC50.orig
1 14.87588 0.515599 14.87588 0.515599
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