build_mydata_clint: Build Data Object for Intrinsic Hepatic Clearance (Clint)...

In invitroTKstats: In Vitro Toxicokinetic Data Processing and Analysis Pipeline

Build Data Object for Intrinsic Hepatic Clearance (Clint) Bayesian Model

Description

Builds a list of arguments required for JAGS from subset of level-2 data frame. The list is used as an argument to JAGS during level-4 processing.

Usage

build_mydata_clint(
  this.cvt,
  this.data,
  decrease.prob,
  saturate.prob,
  degrade.prob
)

Arguments

this.cvt	(Data Frame) Subset of data containing all "Cvst" sample observations of one test compound.
this.data	(Data Frame) Subset of data containing all observations of one test compound.
decrease.prob	(Numeric) Prior probability that a chemical will decrease in the assay.
saturate.prob	(Numeric) Prior probability that a chemicals rate of metabolism will decrease between 1 and 10 uM.
degrade.prob	(Numeric) Prior probability that a chemical will be unstable (that is, degrade abiotically) in the assay.

Value

A named list to be passed into the Bayesian model.

invitroTKstats documentation built on Aug. 23, 2025, 9:08 a.m.