caco2_L0: Caco-2 Level-0 Example Data set
In invitroTKstats: In Vitro Toxicokinetic Data Processing and Analysis Pipeline

caco2_L0

R Documentation

Caco-2 Level-0 Example Data set

Description

A subset of tandem mass spectrometry (MS/MS) measurements of Caco-2 assay-specific data \insertCitehonda2025impactinvitroTKstats. This subset contains samples for 3 test analytes/compounds.

Usage

caco2_L0

Format

A level-0 data.frame with 48 rows and 17 variables:

Compound: Compound name
DTXSID: DSSTox Substance Identifier (CompTox Chemicals Dashboard)
Lab.Compound.ID: Compound ID used in the laboratory
Date: Date MS/MS assay data acquired from instrument
Sample: Sample Name
Type: Type of Caco-2 sample
Compound.Conc: Expected (or nominal) concentration of analyte (for calibration curve)
Peak.Area: Peak area of analyte (target compound)
ISTD.Peak.Area: Peak area of internal standard (pixels)
ISTD.Name: Name of compound used as internal standard (ISTD)
Analysis.Params: General description of chemical analysis method
Level0.File: Name of data file from laboratory that was used to compile level-0 data.frame
Level0.Sheet: Name of "sheet" (for Excel workbooks) from which the laboratory data were read
Direction: Direction of the Caco-2 permeability experiment
Vol.Donor: The media volume (in cm^3) of the donor portion of the Caco-2 experimental well
Vol.Receiver: The media volume (in cm^3) of the receiver portion of the Caco-2 experimental well
Dilution.Factor: Number of times the sample was diluted