pevent: Probability of Having an Event

In lrstat: Power and Sample Size Calculation for Non-Proportional Hazards and Beyond

Probability of Having an Event

Description

Obtains the probability of having an event at given analysis times.

Usage

pevent(
  time = NA_real_,
  piecewiseSurvivalTime = 0L,
  lambda = NA_real_,
  gamma = 0L
)

Arguments

time	A vector of analysis times at which to calculate the probability of having an event.
piecewiseSurvivalTime	A vector that specifies the starting time of piecewise exponential survival time intervals. Must start with 0, e.g., c(0, 6) breaks the time axis into 2 event intervals: [0, 6) and [6, Inf). Defaults to 0 for exponential distribution.
lambda	A vector of hazard rates for the event. One for each analysis time interval.
gamma	The hazard rate for exponential dropout, or a vector of hazard rates for piecewise exponential dropout.

Value

A vector of probabilities of having an event at the specified analysis times after enrollment for a patient in a treatment group with specified piecewise exponential survival and dropout distributions.

Author(s)

Kaifeng Lu, [e-mail]

Examples

# Piecewise exponential survival with hazard 0.0533 in the first 6
# months, and hazard 0.0309 thereafter, and 5% dropout by the end of
# 1 year.

pevent(time = c(3, 9), piecewiseSurvivalTime = c(0, 6),
       lambda = c(0.0533, 0.0309), gamma = -log(1-0.05)/12)

lrstat documentation built on Oct. 18, 2024, 9:06 a.m.