Enzyme: Enzymatic activity in the blood

In mixAK: Multivariate Normal Mixture Models and Mixtures of Generalized Linear Mixed Models Including Model Based Clustering

Enzymatic activity in the blood

Description

Enzymatic activity in the blood, for an enzyme involved in the metabolism of carcinogenic substances, among a group of 245 unrelated individuals.

Bechtel et al. (1993) identified a mixture of two skewed distributions by using maximum-likelihood estimation. Richardson and Green (1997) used a normal mixture estimated using reversible jump MCMC to estimate the distribution of the enzymatic activity.

Usage

data(Enzyme)

Format

A numeric vector with observed values.

Source

Originally from http://www.stats.bris.ac.uk/~peter/mixdata/

References

\mbox{Bechtel, Y. C., Bona\"{\i}ti-Pelli\'e, C., Poisson, N., Magnette, J., and Bechtel, P. R.}(1993). A population and family study of N-acetyltransferase using caffeine urinary metabolites. Clinical Pharmacology and Therapeutics, 54, 134–141.

Richardson, S. and Green, P. J. (1997). On Bayesian analysis of mixtures with unknown number of components (with Discussion). Journal of the Royal Statistical Society, Series B, 59, 731–792.

Examples

data(Enzyme)
summary(Enzyme)

mixAK documentation built on Sept. 25, 2023, 5:08 p.m.