setCov: Set the covariance type based on prior calculated covariances

In nlmixr2est: Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines

Set the covariance type based on prior calculated covariances

Description

Switches a completed fit's covariance to method. A previously computed covariance is re-installed from the cache; otherwise it is recomputed at the converged estimates: "r,s"/"r"/"s" and "analytic" on a zero-iteration FOCEI model, and "sa" (SAEM Louis FIM) / "imp" (importance-sampling Monte-Carlo) via the decoupled recompute engine (the latter two require a mixed-effects fit). When "sa"/"imp"/"analytic" cannot be computed the covariance is left unchanged (it is never silently downgraded to "r,s").

Usage

setCov(fit, method)

Arguments

fit	nlmixr2 fit
method	covariance method (see the 'covMethod' argument for the control options for the choices)

Value

Fit object with covariance updated

Author(s)

Matt Fidler

See Also

foceiControl(), saemControl()

nlmixr2est documentation built on Aug. 5, 2026, 1:11 a.m.