summary.candes: Population Genetic Parameters at Different Times

Description Usage Arguments Details Value Author(s) Examples

Description

For every time point (age cohort), several population genetic parameters are estimated. These may include the generation interval, the average kinship, the average native kinship, the native effective size (native Ne), and the native genome equivalent (NGE) of the population at that point in time.

Usage

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## S3 method for class 'candes'
summary(object, tlim=range(object$phen$Born, na.rm=TRUE), 
     histNe=NA, base=tlim[1], df=4, ...)

Arguments

object

R-Object created with function candes containing phenotypes and kinship information on individuals from the same breed. Data frame cand$phen has columns Indiv (with IDs of the individuals), Born (with the years-of-birth or generation-numbers), Sex, I (average age of the parents at date of birth), and Offspring (indicating if the individual has offspring). Typically function prePed is used to create them. For computing the native Ne the individuals must be from different age cohorts.

tlim

Numeric vector with 2 components giving the time span for which genetic parameters are to be computed.

histNe

The historic effective size of the population assumed for the time between year base and tlim[1], which affects the NGE.

base

The base year in which individuals are assumed to be unrelated. The base year affects the NGE. The default is tlim[1].

df

Smoothing parameter used for computing the native effective size. The default is df=4.

...

further arguments passed to or from other methods

Details

For every time point (age cohort), several population genetic parameters are estimated. These may include the generation interval, the average kinship, the average native kinship, the native effective size (native Ne), and the native genome equivalent (NGE) of the population at that point in time. The population at a time t consists of all individuals born between t-I and t, where I is the generation interval. The population genetic parameters are described below.

Value

A data frame providing for each time point (age cohort) several population genetic parameters. These may include

t

The age cohort, containing e.g. year-of-birth or the generation number. These are the levels of column Born from data frame cand$phen.

I

The estimated generation interval at the time when the individuals were born.

KIN

The average kinship KIN in the population at the time when the individuals were born, where KIN is the name of a kinship. It is an estimate of the probability that 2 alleles chosen from the population are IBD.

NATKIN

The average native kinship NATKIN in the population at the time when the individuals were born, where NATKIN is the name of a native kinship. It is an estimate of the conditional probability that 2 alleles chosen from the population are IBD, given that both are from native ancestors.

Ne

The native effective size of the population at the time when the individuals were born. The native effective size, quantifies how fast the smoothed native kinship is increasing. The native kinship may decrease for a short time span, in which case the estimate would be NA. Use a smaller value for parameter df to get a smoother estimate.

NGE

The native genome equivalents of the population at the time when the individuals were born. The NGE estimates the number of unrelated individuals that would be needed to establish a hypothetical new population that has the same genetic diversity at native alleles as the population under study, whereby the individuals born in the base-year are assumed to be unrelated.

Author(s)

Robin Wellmann

Examples

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data(ExamplePed)
Pedig   <- prePed(ExamplePed, thisBreed="Hinterwaelder", lastNative=1970)
phen    <- Pedig[Pedig$Breed=="Hinterwaelder",]
pKin    <- pedIBD(Pedig)
pKinatN <- pedIBDatN(Pedig, thisBreed="Hinterwaelder")
pop     <- candes(phen=phen, pKin=pKin, pKinatN=pKinatN, quiet=TRUE, reduce.data=FALSE)
Param   <- summary(pop, tlim=c(1970,1995), histNe=150, base=1800, df=4)

plot(Param$t, Param$pKinatN,type="l", ylim=c(0,0.1))
lines(Param$t,Param$pKin, col="red")

plot(Param$t, Param$Ne,  type="l", ylim=c(0,100))
plot(Param$t, Param$NGE, type="l", ylim=c(0,10))
plot(Param$t, Param$I,   type="l", ylim=c(0,10))

optiSel documentation built on Jan. 16, 2021, 5:30 p.m.